Hardware wise we are spec'd to run 3 Zones at once (1 Active Zone, 1 Zone For Water Hammer (only if enabled in device settings), 1 Master Valve).
So if you are driving two valves at once, AND have water hammer enabled, AND have a master valve you would be exceeding the spec.
If you just are running two zones it should be fine.
The only other consideration is the drop in water pressure from driving two zones at once. A lot of irrigation systems can't water two zones at once due to water pressure.
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